No One Can Do What We Do
Our Enzyme Development & Manufacturing business model is cutting edge – no one in the world can do what we do in the way that we do it. People will say that we can’t, but a key function of this site is to let you know that we can.Read more
The Enzyme Development & Manufacture Process
Desk Based Feasibility
The first stage in this process involves assessing the feasibility of the whole project not just technically, but commercially. As an enzyme development and manufacturing company, our overall aim is to provide a continuous supply of your desired novel enzyme at the right price.
Our commercially focused approach, from concept to routine manufacture of bespoke enzyme products, enables us to mitigate risks by developing an enzyme process that is technically and commercially robust. We call this our“Design for Manufacture” approach.
The effectiveness of our “Design for Manufacture” approach is highlighted here, as the sample will be developed using techniques which are fully scalable. Our analysis of the technical aspects of the enzyme use actual production data from our production plant rather than theoretical maxima. This provides peace of mind for the customer.
These projects are run by a team of qualified project managers together with PhD level molecular biologists and fermentation scientists who have many years of enzyme experience.
Bioinformatics & Cloning
Biocatalysts can turn a concept into a reality in just 8 weeks, delivering a sample of active, soluble enzyme along with a technical summary and specification.
Having a small sample of the enzyme allows you to assess whether the enzyme does what it needs to do.
This enzyme sample will be provided with an activity specification, using over 30 years of Biocatalysts assay validation skills. It is also possible to develop a full activity specification if required.
The short timescale on our sample service, compared to the typical 18 month timescale of other enzyme manufacturing companies, ultimately reduces your time to market, allowing for your unique product to be developed and begin delivering profit when you want it.
Fermentation Development, Optimisation & Scale-up
Now that the enzyme has been shown to perform as expected, the final stage involves making the product fit your commercial requirements.
As a leading enzyme development and manufacturing company, we believe the best conditions for the process are identified using a combination of “Design of Experiment” and state of the art parallel micro-fermentation technology. These conditions are then confirmed on a larger scale. This stage only takes 8-12 weeks.
The overall output is a fully scalable, optimised enzyme production process which is designed for routine manufacture. At the end of this stage, the enzyme can be produced at commercial volumes.
Validation, Regulations, Quality Assurance and Routine Manufacture
The output of our unique enzyme development and manufacturing process is the routine manufacture or supply of your exclusive and commercially viable enzyme. This includes all the benefits of being a Biocatalysts standard enzyme product:
- Fully confidential service
- Global shipment
- Regulatory support
- Kosher & Halal certified manufacturing facilities
- Full certification & quality control
- Technical support
As part of our enzyme manufacturing process the enzyme will go through an appropriate pilot scale (500 – 3000L). We have a fermentation capacity of up to 20,000L and full downstream processing capabilities to ensure your desired scale is achieved. The output of this stage is fully saleable product.